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How much can these cells expand - would
one donation of brain tissue
be able to help treat one or more patients with a neurodegenerative
disease?
The number of viable neural precursors that can be harvested
from a given amount of tissue seems to be dependent on a number
of different factors, many of which are incompletely understood.
It is safe to say that a given harvested population can go
through 20-40 doublings in number.
Therefore, the more tissue that is used for the harvest,
the more cells can be generated. What is not known, however,
is the number of cells that would be required to treat a given
patient with a given disease of a given severity. However,
it may be reasonably theorized that at the very least, the
donation of one brain would be sufficient to treat one patient.
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