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Can we assume donation of pediatric brain tissue for this work would likely be handled similarly to current organ donation procedures? Are there any current legal or other precursors that need to be cleared?

While NIH has defined the guidelines to be used when harvesting neural stem cells from prenatal tissue sources, there are no guidelines concerning post-natal tissue sources. Thus, the donation of tissues from any patient population for the purpose of neural precursor harvest and possible transplantation falls under the rubric of existing guidelines. The guidelines mandate the inclusion of language in the consent forms that clearly states that the purposes for which the tissue may be used, including transplantation. At the present time, however, the tissue is only being harvested for research purposes.

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